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Anti-BCMA [I09]

Product Specifications

Gene Name

[BCMA]

NCBI Gene ID

608

Reactivity

Human, Cynomolgus Monkey

Storage Conditions

Store at 4 °C for up to 3 months. For longer storage, aliquot and store at -20 °C.

Specificity

This antibody binds human and cynomolgus monkey BCMA. It acts as a receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. BCMA expression is highest on terminally differentiated B cells. BCMA is involved in mediating the survival of plasma cells for maintaining long-term humoral immunity. It also activates NF-kappa-B and JNK. The expression of BCMA has been linked to a number of cancers, autoimmune disorders, and infectious diseases.

Other Gene Names

[TNFRSF17; TNFRSF17; BCM; BCMA; CD269; TNFRSF13A; BCM; BCMA]

Short Name

[BCMA]

Other Product Names

[tumor necrosis factor receptor superfamily member 17; Tumor necrosis factor receptor superfamily member 17; tumor necrosis factor receptor superfamily member 17; B cell maturation antigen; B-cell maturation factor; B-cell maturation protein; tumor necrosis factor receptor superfamily, member 17; B-cell maturation protein; CD_antigen: CD269]

NCBI GI Number

23238192

NCBI Accession Number

NP_001183.2

NCBI GB Accession Number

NM_001192.2

Uniprot Accession Number

Q02223

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