Anti-TREM-1 [14F69]
Product Specifications
Gene Name
[TREM-1]
NCBI Gene ID
54210
Reactivity
Human, Cynomolgus Monkey, Rhesus Monkey
Storage Conditions
Store at 4 °C for up to 3 months. For longer storage, aliquot and store at -20 °C.
Specificity
This antibody binds human, cynomolgus monkey and rhesus monkey TREM-1. TREM1 is a receptor that is expressed on monocytes, macrophages, neutrophils and dendritic cells. It plays important roles in innate and adaptive immunity by amplifying inflammatory responses. When activated, TREM-1 associates with the ITAM-containing signaling adaptor protein, DAP12. Downstream signalling may include activation of the NFAT transcription factor, causing an upregulation of pro-inflammatory cytokine production.
Other Gene Names
[TREM1; TREM1; CD354; TREM-1; TREM-1]
Short Name
[TREM-1]
Other Product Names
[triggering receptor expressed on myeloid cells 1 isoform 2; Triggering receptor expressed on myeloid cells 1; triggering receptor expressed on myeloid cells 1; triggering-receptor TREM1; triggering receptor expressed on monocytes 1; triggering receptor expressed on myeloid cells 1; Triggering receptor expressed on monocytes 1]
NCBI GI Number
336088680
NCBI Accession Number
NP_001229518.1
NCBI GB Accession Number
NM_001242589.1
Uniprot Accession Number
Q9NP99
Available Sizes
Curated Selection
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