Anti-TREM-1 [14F69]

Product Specifications

Gene Name

[TREM-1]

NCBI Gene ID

54210

Reactivity

Human, Cynomolgus Monkey, Rhesus Monkey

Storage Conditions

Store at 4 °C for up to 3 months. For longer storage, aliquot and store at -20 °C.

Specificity

This antibody binds human, cynomolgus monkey and rhesus monkey TREM-1. TREM1 is a receptor that is expressed on monocytes, macrophages, neutrophils and dendritic cells. It plays important roles in innate and adaptive immunity by amplifying inflammatory responses. When activated, TREM-1 associates with the ITAM-containing signaling adaptor protein, DAP12. Downstream signalling may include activation of the NFAT transcription factor, causing an upregulation of pro-inflammatory cytokine production.

Other Gene Names

[TREM1; TREM1; CD354; TREM-1; TREM-1]

Short Name

[TREM-1]

Other Product Names

[triggering receptor expressed on myeloid cells 1 isoform 2; Triggering receptor expressed on myeloid cells 1; triggering receptor expressed on myeloid cells 1; triggering-receptor TREM1; triggering receptor expressed on monocytes 1; triggering receptor expressed on myeloid cells 1; Triggering receptor expressed on monocytes 1]