Anti-Norovirus capsid protein VP1 [A1227]

This antibody shows broadly binding but no blocking activity toward multiple GI and GII strains such as GI.I, GII.2, and GII.17. This antibody recognizes a highly conserved epitope located at an occluded site on the norovirus capsid, at the interface between the P domain and shell domain of the Norovirus, which explain its high level of cross-reactivity. Norovirus (NoVs) is one of the main pathogens causing sporadic cases and large outbreaks of acute gastroenteritis, and norovirus can infect people of all ages.

[nonstructural polyprotein; Genome polyprotein; nonstructural polyprotein; p48; NTPase; p22; VPg; Pro; RdRp; Protein p48NTPase (EC:3.6.1.15)Alternative name(s):p41]