Dinutuximab
Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions of human IgG1 heavy-chain and kappa light-chain
Product Specifications
Product Name Alternative
14.18, MAb-14.18, MOAB Ch14.18
Reactivity
Human
Target
Ganglioside GD2
Clonality
Monoclonal
Conjugation
Unconjugated
Source
CHO cells
Purity
> 95%
Molecular Weight
145000.0 Da
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at +4°C short term (1-2 weeks) . Store at -20 °C 12 months. Store at -80°C long term
Notes
For research use only.
Tested Applications
SDS-PAGE
Host or Source
Mouse
Preservative
PBS buffer pH 7.5
Isotype
IgG1-kappa
Available Sizes
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