DJ101
Product Specifications
UNSPSC Description
DJ101 is a potent and metabolically stable tubulin inhibitor. DJ101 targets the colchicine binding site and overcomes taxane resistance. DJ101 also inhibits melanoma tumor growth and lung metastasis. DJ101 can be used for prostate cancer research[1].
Target Antigen
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dj101.html
Purity
99.36
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=C(OC)C(OC)=CC(C2=NC=CC3=C2N=C(C4=CC=CC5=C4C=CN5)N3)=C1
Molecular Weight
400.43
References & Citations
[1]Arnst KE, Wang Y, Hwang DJ, et al. A Potent, Metabolically Stable Tubulin Inhibitor Targets the Colchicine Binding Site and Overcomes Taxane Resistance. Cancer Res. 2018;78(1):265-277.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-121524/DJ101-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-121524/DJ101-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1803242-21-8
Available Sizes
Curated Selection
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