HAT Assay Buffer 5X (Biotechnology Grade)

<strong>HAT Assay Buffer 5X</strong>_x000D_ <strong>Catalog number:</strong> B2010130_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 2 mL_x000D_ <strong>pH:</strong> 8_x000D_ <strong>Supplied as:</strong> 5X Concentrate (Dilute 1:5 before use)_x000D_ <strong>Appearance:</strong> Clear solution_x000D_ <strong>Applications:</strong> optimized buffer for histone acetyltransferase (HAT) assays._x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> HAT buffer, histone acetyltransferase assay, cell-based assay development_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered on a 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Su J, Wang F, Cai Y, Jin J. The Functional Analysis of Histone_x000D_ Acetyltransferase MOF in Tumorigenesis. Int J Mol Sci. 2016 Jan 14;17(1):99._x000D_ _x000D_ 2: Voss AK, Thomas T. Histone Lysine and Genomic Targets of Histone_x000D_ Acetyltransferases in Mammals. Bioessays. 2018 Oct;40(10):e1800078._x000D_ _x000D_ 3: Baell JB, Miao W. Histone acetyltransferase inhibitors: where art thou?_x000D_ Future Med Chem. 2016 Sep;8(13):1525-8._x000D_ _x000D_ 4: Yin Z, Chen C, Yang J, Feng W, Liu X, Zuo R, Wang J, Yang L, Zhong K, Gao C,_x000D_ Zhang H, Zheng X, Wang P, Zhang Z. Histone acetyltransferase MoHat1 acetylates_x000D_ autophagy-related proteins MoAtg3 and MoAtg9 to orchestrate functional_x000D_ appressorium formation and pathogenicity in <i>Magnaporthe oryzae</i>._x000D_ Autophagy. 2019 Jul;15(7):1234-1257._x000D_ _x000D_ 5: Dubey A, Lee J, Kwon S, Lee YH, Jeon J. A MYST family histone_x000D_ acetyltransferase, MoSAS3, is required for development and pathogenicity in the_x000D_ rice blast fungus. Mol Plant Pathol. 2019 Nov;20(11):1491-1505._x000D_ _x000D_ 6: Lasko LM, Jakob CG, Edalji RP, Qiu W, Montgomery D, Digiammarino EL, Hansen_x000D_ TM, Risi RM, Frey R, Manaves V, Shaw B, Algire M, Hessler P, Lam LT, Uziel T,_x000D_ Faivre E, Ferguson D, Buchanan FG, Martin RL, Torrent M, Chiang GG, Karukurichi_x000D_ K, Langston JW, Weinert BT, Choudhary C, de Vries P, Van Drie JH, McElligott D,_x000D_ Kesicki E, Marmorstein R, Sun C, Cole PA, Rosenberg SH, Michaelides MR, Lai A,_x000D_ Bromberg KD. Discovery of a selective catalytic p300/CBP inhibitor that targets_x000D_ lineage-specific tumours. Nature. 2017 Oct 5;550(7674):128-132._x000D_ _x000D_ 7: Martin BJ, McBurney KL, Maltby VE, Jensen KN, Brind'Amour J, Howe LJ. Histone_x000D_ H3K4 and H3K36 Methylation Independently Recruit the NuA3 Histone_x000D_ Acetyltransferase in <i>Saccharomyces cerevisiae</i>. Genetics. 2017_x000D_ Mar;205(3):1113-1123._x000D_ _x000D_ 8: Han J, Lachance C, Ricketts MD, McCullough CE, Gerace M, Black BE, Côté J,_x000D_ Marmorstein R. The scaffolding protein JADE1 physically links the_x000D_ acetyltransferase subunit HBO1 with its histone H3-H4 substrate. <a href="https://pubmed.ncbi.nlm.nih.gov/29382722/">J Biol Chem</a>._x000D_ 2018 Mar 23;293(12):4498-4509._x000D_ _x000D_ <strong>Products Related to HAT Assay Buffer 5X </strong> <a>Biochemical Buffers and Solutions</a>