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Ac-PPPHPHARIK-NH2

Ac-PPPHPHARIK-NH2 (compound S1) is a compound that inhibits the interaction between androgen receptor and Src. It can inhibit the binding of androgen or estrogen-induced receptor and Src in cancer cells, as well as the activation of related signaling pathways, and can also inhibit cell cycle progression and tumor growth.

Product Specifications

CAS Number

957791-38-7

UNSPSC

12352209

Target

Androgen Receptor; Src

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK; Vitamin D Related/Nuclear Receptor

Applications

Cancer-Kinase/protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ac-ppphpharik-nh2.html

Smiles

O=C(N1[C@@H](CCC1)C(N[C@@H](CC2=CN=CN2)C(N3[C@@H](CCC3)C(N[C@H](C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(N)=O)CCCCN)=O)=O)=O)=O)CC4=CN=CN4)=O)=O)=O)[C@H]5N(CCC5)C([C@H]6N(CCC6)C(C)=O)=O

Molecular Formula

C55H87N19O11

Molecular Weight

1190.40

References & Citations

[1]Inhibition of the SH3 domain-mediated binding of Src to the androgen receptor and its effect on tumor growth

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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