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Ac-PPPHPHARIK-NH2

Ac-PPPHPHARIK-NH2 (compound S1) is a compound that inhibits the interaction between androgen receptor and Src. It can inhibit the binding of androgen or estrogen-induced receptor and Src in cancer cells, as well as the activation of related signaling pathways, and can also inhibit cell cycle progression and tumor growth.

Product Specifications

CAS Number

[957791-38-7]

UNSPSC

12352209

Target

Androgen Receptor; Src

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK; Vitamin D Related/Nuclear Receptor

Applications

Cancer-Kinase/protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ac-ppphpharik-nh2.html

Smiles

O=C(N1[C@@H](CCC1)C(N[C@@H](CC2=CN=CN2)C(N3[C@@H](CCC3)C(N[C@H](C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(N)=O)CCCCN)=O)=O)=O)=O)CC4=CN=CN4)=O)=O)=O)[C@H]5N(CCC5)C([C@H]6N(CCC6)C(C)=O)=O

Molecular Formula

C55H87N19O11

Molecular Weight

1190.40

References & Citations

[1]Inhibition of the SH3 domain-mediated binding of Src to the androgen receptor and its effect on tumor growth

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P2413/Ac-PPPHPHARIK-NH2-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P2413/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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