MRS8028
MRS8028 is an agonist for A3 adenosine receptor (A3AR), which binds hA3AR with Ki of 2.44 nM. MRS8028 is potential for ameliorating ischemia and inflammatory diseases[1].
Product Specifications
CAS Number
[1784714-67-5]
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mrs8028.html
Smiles
O[C@@H]1[C@H](O)[C@@]2(C(NC)=O)[C@H](C2)[C@H]1N3C=NC4=C3N=C(C#CC5=CC=C(Cl)S5)N=C4NCC
Molecular Formula
C21H21ClN6O3S
Molecular Weight
472.95
References & Citations
[1]Tosh D K, et al. 2-Substituted (N) -Methanocarba A3 Adenosine Receptor Agonists: In Silico, In Vitro, and In Vivo Characterization[J]. ACS Pharmacology & Translational Science, 2024.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161718/MRS8028-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161718/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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