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RVD-Hpα

RVD-Hpα, an α-hemoglobin-derived peptide containing three additional amino acids, is a CB1 cannabinoid receptor agonist. RVD-Hpα is a positive allosteric modulator of cannabinoid receptor 2[1][2].

Product Specifications

CAS Number

1193362-76-3

UNSPSC

12352209

Target

Cannabinoid Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rvd-hpα.html

Solubility

10 mM in DMSO

Smiles

N=C(N)NCCC[C@H](N)C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(N1[C@@H](CCC1)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@H](C(O)=O)CC2=CN=CN2)=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)=O

Molecular Formula

C65H105N19O17

Molecular Weight

1424.65

References & Citations

[1]Ivone Gomes, et al. Novel endogenous peptide agonists of cannabinoid receptors. FASEB J. 2009 Sep;23 (9) :3020-9.|[2]Fengmei Wei, et al. Hemoglobin-derived peptides and mood regulation. Peptides. 2020 Feb 15;127:170268.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

CB1

Frequently Asked Questions

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