Recombinant Human Chromogranin A
Recombinant Human Chromogranin A
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
CHGA
UniProt
P10645
Reactivity
Human
Target Antigen
Chromogranin-A
Target
Chromogranin A
Type
Protein
Applications
WB
Concentration
Lot Specific
Dilution
Dilute in PBS or medium that is identical to that used in the assay system.
Form
Liquid
Buffer
20 mM Tris
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store at or below -20°C for longer periods of time. Addition of a carrier protein (such as 0.1% HSA or BSA) is recommended for long-term storage.
Specificity
Chromogranin A
Formulation
Sterile-filtered solution in 20mM Tris-HCl, pH 8.0, and 10% glycerol.
Buffer pH
pH 8.0
Target Background
Chromogranin A (CHGA) is a member of the neuroendocrine secretory protein family located in secretory vesicles of neurons and endocrine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides function as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides including chromostatin, betagranin, WE-14 and GE-25 are also derived from full-length CHGA. CHGA has numerous biological activities including antifungal and antimicrobial action, modulation of cell adhesion, and inhibition of parathyroid hormone secretion.
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