3',4'-Dihydroxyflavonol

3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant, which reduces superoxide and improves nitric oxide (NO) function in diabetic rat mesenteric arteries[1].

Product Specifications

CAS Number

[6068-78-6]

Product Name Alternative

DiOHF

UNSPSC

12352005

Hazard Statement

H301

Target

NO Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/3_acute_,4_acute_-Dihydroxyflavonol.html

Purity

99.33

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C1C(O)=C(C2=CC=C(O)C(O)=C2)OC3=C1C=CC=C3

Molecular Formula

C15H10O5

Molecular Weight

270.24

Precautions

H301

References & Citations

[1]Leo CH, et al. 3',4'-Dihydroxyflavonol reduces superoxide and improves nitric oxide function in diabetic rat mesenteric arteries. PLoS One. 2011;6 (6) :e20813.|[2]Kim HY, et al. 3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²⁺ desensitization in permeabilized rat mesenteric artery. Naunyn Schmiedebergs Arch Pharmacol. 2012 Feb;385 (2) :191-202.