Echimidine N-oxide
Echimidine N-oxide, a pyrrolizidine alkaloid, has acetylcholinesterase (AChE) inhibitory activity (IC50=0.347 mM) [1].
Product Specifications
CAS Number
[41093-89-4]
UNSPSC
12352005
Hazard Statement
H300+H310+H330
Target
Cholinesterase (ChE)
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/echimidine-n-oxide.html
Solubility
10 mM in DMSO
Smiles
CC(C)(O)[C@@]([C@@H](O)C)(O)C(OCC1=CC[N+]2([O-])[C@@]1([H])[C@@H](CC2)OC(/C(C)=C\C)=O)=O
Molecular Formula
C20H31NO8
Molecular Weight
413.46
Precautions
P260-P262-P264-P270-P271-P280-P284-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
References & Citations
[1]Houari Benamar, et al. Acetylcholinesterase inhibitory activity of pyrrolizidine alkaloids from Echium confusum Coincy. Nat Prod Res. 2017 Jun;31 (11) :1277-1285.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
AChE
Curated Selection
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