VUF8504
VUF-8504 is a potent and selective adenosine A3 receptor antagonist with Ki value of 0.017, 14 nM for human A3, A1, respectively[1].
Product Specifications
CAS Number
112575-50-5
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/vuf8504.html
Smiles
O=C(C1=CC=C(C=C1)OC)NC2=NC(C3=NC=CC=C3)=CC4=C2C=CC=C4
Molecular Formula
C22H17N3O2
Molecular Weight
355.39
References & Citations
[1]van Muijlwijk-Koezen JE, et al. A novel class of adenosine A3 receptor ligands. 2. Structure affinity profile of a series of isoquinoline and quinazoline compounds. J Med Chem. 1998 Oct 8;41 (21) :3994-4000.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Adenosine A1 receptor (A1R) ; Adenosine A3 receptor (A3R)
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