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(R) -Propranolol (hydrochloride)

(R) -Propranolol hydrochloride is a less active enantiomer of the β-adrenoceptor antagonist propranolol (HY-B0573) . Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively[1].

Product Specifications

CAS Number

[13071-11-9]

UNSPSC

12352005

Hazard Statement

H302

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/r-propranolol-hydrochloride.html

Purity

99.36

Solubility

DMSO : 250 mg/mL (ultrasonic) |H2O : 7.14 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O[C@@H](COC1=C2C=CC=CC2=CC=C1)CNC(C)C.[H]Cl

Molecular Formula

C16H22ClNO2

Molecular Weight

295.80

Precautions

H302

References & Citations

[1]A M Barrett, et al. The biological properties of the optical isomers of propranolol and their effects on cardiac arrhythmias. Br J Pharmacol

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

β adrenergic receptor

Available Sizes

Curated Selection

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