(R) -Propranolol (hydrochloride)
(R) -Propranolol hydrochloride is a less active enantiomer of the β-adrenoceptor antagonist propranolol (HY-B0573) . Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively[1].
Product Specifications
CAS Number
[13071-11-9]
UNSPSC
12352005
Hazard Statement
H302
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/r-propranolol-hydrochloride.html
Purity
99.36
Solubility
DMSO : 250 mg/mL (ultrasonic) |H2O : 7.14 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O[C@@H](COC1=C2C=CC=CC2=CC=C1)CNC(C)C.[H]Cl
Molecular Formula
C16H22ClNO2
Molecular Weight
295.80
Precautions
H302
References & Citations
[1]A M Barrett, et al. The biological properties of the optical isomers of propranolol and their effects on cardiac arrhythmias. Br J Pharmacol
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β adrenergic receptor
Available Sizes
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