Aloeresin D
Aloeresin D is a chromone glycoside isolated from Aloe vera, inhibits β-Secretase (BACE1) activity, with an IC50 of 39 μM[1].
Product Specifications
CAS Number
[105317-67-7]
UNSPSC
12352005
Target
Beta-secretase
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aloeresin-d.html
Purity
99.51
Solubility
DMSO : 250 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 6.67 mg/mL (ultrasonic)
Smiles
O=C1C=C(C[C@H](O)C)OC2=C([C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)OC(/C=C/C4=CC=C(O)C=C4)=O)C(OC)=CC(C)=C12
Molecular Formula
C29H32O11
Molecular Weight
556.56
References & Citations
[1]Lv L, et al. BACE1 (beta-secretase) inhibitory chromone glycosides from Aloe vera and Aloe nobilis. Planta Med. 2008 Apr;74 (5) :540-5.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
BACE1
Available Sizes
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