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LY382884

LY382884 is a selective antagonist for GluR5 kainate receptor. LY382884 prevents the induction of NMDA receptor independent long-term potentiation (LTP) [1].

Product Specifications

CAS Number

[211566-75-5]

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ly382884.html

Solubility

10 mM in DMSO

Smiles

O=C([C@H]1NC[C@]2([H])CC[C@H](CC3=CC=C(C(O)=O)C=C3)C[C@]2([H])C1)O

Molecular Formula

C18H23NO4

Molecular Weight

317.38

References & Citations

[1]Bortolotto ZA, et al., Kainate receptors are involved in synaptic plasticity. Nature. 1999 Nov 18;402 (6759) :297-301.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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