LY382884
LY382884 is a selective antagonist for GluR5 kainate receptor. LY382884 prevents the induction of NMDA receptor independent long-term potentiation (LTP) [1].
Product Specifications
CAS Number
[211566-75-5]
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly382884.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1NC[C@]2([H])CC[C@H](CC3=CC=C(C(O)=O)C=C3)C[C@]2([H])C1)O
Molecular Formula
C18H23NO4
Molecular Weight
317.38
References & Citations
[1]Bortolotto ZA, et al., Kainate receptors are involved in synaptic plasticity. Nature. 1999 Nov 18;402 (6759) :297-301.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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