Mal-amido-PEG4-TFP ester
Mal-amido-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
1807540-84-6
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-amido-peg4-tfp-ester.html
Purity
99.59
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC1=C(F)C(F)=CC(F)=C1F)CCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O
Molecular Formula
C24H28F4N2O9
Molecular Weight
564.48
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers; PEG Linkers
Available Sizes
Frequently Asked Questions
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