κ-Carrageenan
κ-Carrageenan is a natural polymer which predominantly available in red seaweeds. κ-Carrageenan is an effective agent carrier to deliver curcumin in cancer cells and to induce apoptosis. κ-carrageenan serves as a potential inflammatory agent that magnifies existing intestinal inflammation[1][2].
Product Specifications
CAS Number
11114-20-8
Product Name Alternative
K-Carrageenan Karra Type
UNSPSC
12352005
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/κ-carrageenan.html
Solubility
DMSO : 8.33 mg/mL (ultrasonic; warming; heat to 80°C) |H2O : 8 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
[K-Carrageenan]
References & Citations
[1]Sathuvan M, et al. κ-Carrageenan: An effective drug carrier to deliver curcumin in cancer cells and to induce apoptosis. Carbohydr Polym. 2017;160:184-193.|[2]Wu W, et al. κ-Carrageenan Enhances Lipopolysaccharide-Induced Interleukin-8 Secretion by Stimulating the Bcl10-NF-κB Pathway in HT-29 Cells and Aggravates C. freundii-Induced Inflammation in Mice. Mediators Inflamm. 2017;2017:8634865.|[3]Wei W, et al. Enhanced effect of κ-carrageenan on TNBS-induced inflammation in mice. Int Immunopharmacol. 2016;39:218-228.|[4]Morris CJ. Carrageenan-induced paw edema in the rat and mouse. Methods Mol Biol. 2003;225:115-21.|[5]Ochoa-Amaya JE, et al. Dual effects of hyperprolactinemia on carrageenan-induced inflammatory paw edema in rats. Neuroimmunomodulation. 2011;18 (4) :245-53.|[6]Jiang HY, et al. κ-carrageenan induces the disruption of intestinal epithelial Caco-2 monolayers by promoting the interaction between intestinal epithelial cells and immune cells. Mol Med Rep. 2013 Dec;8 (6) :1635-42.|[7]Wei W, et al. Enhanced effect of κ-carrageenan on TNBS-induced inflammation in mice. Int Immunopharmacol. 2016 Oct;39:218-228.|[8]Ma N, et al. Preventive Effect of Aspirin Eugenol Ester on Thrombosis in κ-Carrageenan-Induced Rat Tail Thrombosis Model. PLoS One. 2015 Jul 20;10 (7) :e0133125.|[9]Wang J, et al. Pharmacokinetics, tissue distribution, and subacute toxicity of oral carrageenan in mice. Int J Biol Macromol. 2024 May;266 (Pt 1) :130725.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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