(Rac) -WRC-0571

(Rac) -WRC-0571 is a highly potent, orally active and selective, non-xanthine antagonist of A1 adenosine receptors. (Rac) -WRC-0571 inhibits [3H]-N6-cyclohexyladenosine (CHA) binding to guinea pig A1-receptors with a Ki value of 1.1 nM[1].

Product Specifications

CAS Number

[501667-77-2]

UNSPSC

12352005

Target

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/rac-wrc-0571.html

Smiles

OC1C2CC(C1)C(NC3=C4N=C(N(C4=NC=N3)C)N(C(C)C)C)C2

Molecular Formula

C17H26N6O

Molecular Weight

330.43

References & Citations

[1]P L Martin, et al. Characterization of 8- (N-methylisopropyl) amino-N6- (5'-endohydroxy- endonorbornyl) -9-methyladenine (WRC-0571), a highly potent and selective, non-xanthine antagonist of A1 adenosine receptors. J Pharmacol Exp Ther. 1996 Feb;276 (2) :490-9.