L 368935
L 368935 is a cholecystokinin B receptor (CCKB receptor) antagonist. L 368935 is a brain-penetrant and centrally active compound[1][2].
Product Specifications
CAS Number
145878-31-5
UNSPSC
12352005
Target
Cholecystokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/l-368935.html
Smiles
CC(C)CN1C2=CC=CC=C2C(C3=CC=CC=C3)=N[C@H](C1=O)NC(NC4=CC(C5=NN=NN5)=CC=C4)=O
Molecular Formula
C27H26N8O2
Molecular Weight
494.55
References & Citations
[1]Use of ex vivo binding to estimate brain penetration and central activity of CCK-B antagonists|[2]Patel S, et al. Measurement of central nervous system activity of systemically administered CCKB receptor antagonists by ex vivo binding. Eur J Pharmacol. 1994 Mar 3;253 (3) :237-44.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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