L 368935

L 368935 is a cholecystokinin B receptor (CCKB receptor) antagonist. L 368935 is a brain-penetrant and centrally active compound[1][2].

Product Specifications

CAS Number

[145878-31-5]

UNSPSC

12352005

Target

Cholecystokinin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/l-368935.html

Smiles

CC(C)CN1C2=CC=CC=C2C(C3=CC=CC=C3)=N[C@H](C1=O)NC(NC4=CC(C5=NN=NN5)=CC=C4)=O

Molecular Formula

C27H26N8O2

Molecular Weight

494.55

References & Citations

[1]Use of ex vivo binding to estimate brain penetration and central activity of CCK-B antagonists|[2]Patel S, et al. Measurement of central nervous system activity of systemically administered CCKB receptor antagonists by ex vivo binding. Eur J Pharmacol. 1994 Mar 3;253 (3) :237-44.