Imazodan (hydrochloride)

Imazodan hydrochloride is the hydrochloride form of Imazodan (HY-106045) . Imazodan hydrochloride is a selective inhibitor for phosphodiesterase III (PDE III), which increases myocardial contractility by blocking the cAMP degradation, and improves the contractile function of heart. Imazodan hydrochloride serves also as a peripheral vasodilator[1].

Product Specifications

CAS Number

[89198-09-4]

Product Name Alternative

CI 914

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/imazodan-hydrochloride.html

Smiles

O=C1NN=C(CC1)C2=CC=C(N3C=NC=C3)C=C2.Cl

Molecular Formula

C13H13ClN4O

Molecular Weight

276.72

References & Citations

[1]Goldberg AD, et al., Effectiveness of imazodan for treatment of chronic congestive heart failure. The Imazodan Research Group. Am J Cardiol. 1991 Sep 1;68 (6) :631-6.