Imazodan (hydrochloride)
Imazodan hydrochloride is the hydrochloride form of Imazodan (HY-106045) . Imazodan hydrochloride is a selective inhibitor for phosphodiesterase III (PDE III), which increases myocardial contractility by blocking the cAMP degradation, and improves the contractile function of heart. Imazodan hydrochloride serves also as a peripheral vasodilator[1].
Product Specifications
CAS Number
[89198-09-4]
Product Name Alternative
CI 914
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/imazodan-hydrochloride.html
Smiles
O=C1NN=C(CC1)C2=CC=C(N3C=NC=C3)C=C2.Cl
Molecular Formula
C13H13ClN4O
Molecular Weight
276.72
References & Citations
[1]Goldberg AD, et al., Effectiveness of imazodan for treatment of chronic congestive heart failure. The Imazodan Research Group. Am J Cardiol. 1991 Sep 1;68 (6) :631-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE3
Curated Selection
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