Amodiaquine-d10 (hydrochloride)
Amodiaquine-d10 hydrochloride is deuterated labeled Amodiaquine. Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect[1][2][3][4].
Product Specifications
Product Name Alternative
Amodiaquin-d10
UNSPSC
12352005
Target
Histone Methyltransferase; Isotope-Labeled Compounds; Nuclear Hormone Receptor 4A/NR4A; Parasite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Epigenetics; Others; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology; Neurological Disease
Solubility
10 mM in DMSO
Smiles
ClC(C=C1)=CC2=C1C(NC3=CC(CN(C([2H])([2H])C([2H])([2H])[2H])C([2H])([2H])C([2H])([2H])[2H])=C(C=C3)O)=CC=N2.Cl.Cl
Molecular Formula
C20H14D10Cl3N3O
Molecular Weight
438.84
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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