HSD17B13-IN-52
HSD17B13-IN-52 (Compound 84) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-52 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI) [1].
Product Specifications
CAS Number
2770246-77-8
UNSPSC
12352005
Target
17β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hsd17b13-in-52.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(Cl)=C(C(Cl)=C1)O)NC2=CC=CC(N=CN3CC4=C(N5CCOCC5)C=CC=C4)=C2C3=O
Molecular Formula
C26H22Cl2N4O4
Molecular Weight
525.38
References & Citations
[1]Anandan S K, et al. Dichlorophenol HSD17B13 inhibitors and uses thereof. U.S., WO2022103960. 2023-11-28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![DNAAF11 Mouse Monoclonal Antibody [Clone ID: OTI2F8]](https://cdn.genprice.uk/products/937/68dd18b9061270361e907e0b/imageurl/cf805964.webp)
DNAAF11 Mouse Monoclonal Antibody [Clone ID: OTI2F8]
![TNFRSF4 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1B10]](https://cdn.genprice.uk/products/937/6868c40b994c49e6dc40594a/imageurl/ta812357am.webp)