(E) -8- (3-Chlorostyryl) caffeine
(E) -8- (3-Chlorostyryl) caffeine is a selective adenosine A2A receptor antagonist. (E) -8- (3-Chlorostyryl) caffeine inhibits monoamine oxidase B (MAO-B) with a Ki value of 70 nM by a pathway that is independent of its actions on the A2A receptor. (E) -8- (3-Chlorostyryl) caffeine has the potential for Parkinson's disease research[1].
Product Specifications
CAS Number
[147700-11-6]
UNSPSC
12352005
Target
Adenosine Receptor; Monoamine Oxidase
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/e-8-3-chlorostyryl-caffeine.html
Purity
99.4
Solubility
DMSO : 8.27 mg/mL (ultrasonic; warming)
Smiles
CN1C2=C(N(C(N(C2=O)C)=O)C)N=C1/C=C/C3=CC(Cl)=CC=C3
Molecular Formula
C16H15ClN4O2
Molecular Weight
330.77
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Adenosine A2A receptor (A2AR) ; MAO-B
Available Sizes
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