Procyclidine (hydrochloride)

Procyclidine (Tricyclamol, (±) -Procyclidine) hydrochloride , an anticholinergic agent, is a muscarinic receptor antagonist that also has the properties of an N-methyl-D-aspartate (NMDA) antagonist. Procyclidine hydrochloride can be used in studies of Parkinson's disease and related psychiatric disorders such as Soman-induced epilepsy[1][2].

Product Specifications

CAS Number

[1508-76-5]

Product Name Alternative

Tricyclamol (hydrochloride) ; (±) -Procyclidine (hydrochloride)

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

IGluR; mAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Procyclidine-hydrochloride.html

Purity

99.55

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 5.56 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC(C1=CC=CC=C1)(C2CCCCC2)CCN3CCCC3.[H]Cl

Molecular Formula

C19H30ClNO

Molecular Weight

323.90

Precautions

H315, H319, H320

References & Citations

[1]Yun-Bae Kim, et al. Effects of combinational prophylactics composed of physostigmine and procyclidine on soman-induced lethality, seizures and brain injuries. Environ Toxicol Pharmacol. 2002 Jan;11 (1) :15-21.|[2]Ulrich Ettinger, et al. Effects of procyclidine on eye movements in schizophrenia. Neuropsychopharmacology. 2003 Dec;28 (12) :2199-208.