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Calcitonin, porcine

Calcitonin, porcine inhibits 1,25 (OH) 2D3-stimulated porcine osteoclast differentiation. Calcitonin is a polypeptide hormone that can lower serum calcium by decreasing calcium reabsorption in the kidney and inhibiting osteoclastic bone resorption. Calcitonin, porcine can be used for research of hypercalcemia[1][2].

Product Specifications

CAS Number

12321-44-7

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/calcitonin-porcine.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@H]1[C@H](O)C)=O)=O)=O)=O)[C@H](CSSC[C@@H](C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CC6=CNC=N6)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC7=CC=CC=C7)C(N[C@@H](CO)C(NCC(N[C@@H](CCSC)C(NCC(N[C@@H](CC8=CC=CC=C8)C(NCC(N9[C@@H](CCC9)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](O)C)C(N%10[C@@H](CCC%10)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC1=O)N

Molecular Formula

C159H232N46O45S3

Molecular Weight

3604.02

References & Citations

[1]Galvin RJ, et al. Calcitonin responsiveness and receptor expression in porcine and murine osteoclasts: a comparative study. Bone. 1998 Sep;23 (3) :233-40. |[2]Kammerman S, et al. Effect of porcine calcitonin on hypercalcemia in man. J Clin Endocrinol Metab. 1970 Jul;31 (1) :70-5.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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