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Ethacridine (lactate monohydrate)

Ethacridine lactate (Acrinol) monohydrate is a widely used antiseptic and abortifacient. Ethacridine lactate monohydrate is effective against Staphylococcus aureus and other gram-positive cocci. Ethacridine lactate monohydrate is also a poly (ADP-ribose) glycohydrolase (PARG) inhibitor[1][2][3].

Product Specifications

CAS Number

6402-23-9

Product Name Alternative

Acrinol (monohydrate)

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Ethacridine-lactate-monohydrate.html

Purity

99.85

Solubility

DMSO : ≥ 100 mg/mL|H2O : 2 mg/mL (ultrasonic)

Smiles

CC(O)C(O)=O.NC1=CC2=NC3=CC=C(OCC)C=C3C(N)=C2C=C1.O

Molecular Formula

C18H23N3O5

Molecular Weight

361.39

Precautions

H315, H319, H335

References & Citations

[1]Rotin LE, et al. Erlotinib synergizes with the poly (ADP-ribose) glycohydrolase inhibitor ethacridine in acute myeloid leukemia cells. Haematologica. 2016 Nov;101 (11) :e449-e453.|[2]Gupta S, et, al. Ethacridine lactate -- a safe and effective drug for termination of pregnancy. Indian J Matern Child Health. 1993;4 (2) :59-61.|[3]Usuki R, et, al. Antibacterial Activity of Acrinol against Organisms Isolated from Clinical Materials and Influence of Light on Antibacterial Activity of Acrinol. Japanese Journal of Pharmaceutical Health Care and Sciences. 2004 Jan; 30 (2) :72-77.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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