Azadiradione
Azadiradione is a bioactive limonoid found in Azadirachta indica. Azadiradione is a HSF1 activator. Azadiradione has antimycobacterial, anti-nociceptive and anti-inflammatory activities[1][2].
Product Specifications
CAS Number
26241-51-0
UNSPSC
12352005
Target
HSP
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/azadiradione.html
Solubility
10 mM in DMSO
Smiles
C[C@]12C([C@]([C@]3([H])C4=COC=C4)(CC[C@]1([H])[C@@]5([C@@](C(C)(C(C=C5)=O)C)([H])C[C@H]2OC(C)=O)C)C)=CC3=O
Molecular Formula
C28H34O5
Molecular Weight
450.57
References & Citations
[1]K Ilango, et al. Anti-nociceptive and anti-inflammatory activities of Azadirachta indica fruit skin extract and its isolated constituent azadiradione. Nat Prod Res. 2013;27 (16) :1463-7. |[2]Brijesh Kumar Singh, et al. Azadiradione Restores Protein Quality Control and Ameliorates the Disease Pathogenesis in a Mouse Model of Huntington's Disease. Mol Neurobiol. 2018 Aug;55 (8) :6337-6346.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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