KS124
KS124 (compound 3) is a potent ALDH inhibitor. KS124 shows inhibition for ALDH1A1, ALDH1A3, ALDH3A1. KS124 shows antiproliferative activity. KS124 induces apoptosis and ROS production[1].
Product Specifications
UNSPSC
12352005
Target
Aldehyde Dehydrogenase (ALDH) ; Apoptosis; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ks124.html
Smiles
O=C(C1=CC=C([N+]([O-])=O)O1)OCC2=CC=C(CN3C(C(C4=C3C(Br)=CC(Br)=C4)=O)=O)C=C2
Molecular Formula
C21H12Br2N2O7
Molecular Weight
564.14
References & Citations
[1]Gowda K, et al. Identification of Novel Isatin Derivative Bearing a Nitrofuran Moiety as Potent Multi-Isoform Aldehyde Dehydrogenase Inhibitor. Molecules. 2024 Jun 29;29 (13) :3114.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
P4214-32B 50 µg
Plectin (PLTN, PCN, Hemidesmosomal Protein 1, HD1, PLEC1) discontinued
Sign In for Pricing
View Details 
MBS2087445-01 24 Strip Well
Bovine Immunoglobulin G (IgG) Mini Samples ELISA Kit
Sign In for Pricing
View Details MBS2087445-02 48 Well
Bovine Immunoglobulin G (IgG) Mini Samples ELISA Kit
Sign In for Pricing
View Details MBS2087445-03 96 Well
Bovine Immunoglobulin G (IgG) Mini Samples ELISA Kit
Sign In for Pricing
View Details MBS2087445-04 5x 96 Well
Bovine Immunoglobulin G (IgG) Mini Samples ELISA Kit
Sign In for Pricing
View Details