KS124
KS124 (compound 3) is a potent ALDH inhibitor. KS124 shows inhibition for ALDH1A1, ALDH1A3, ALDH3A1. KS124 shows antiproliferative activity. KS124 induces apoptosis and ROS production[1].
Product Specifications
UNSPSC
12352005
Target
Aldehyde Dehydrogenase (ALDH) ; Apoptosis; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ks124.html
Smiles
O=C(C1=CC=C([N+]([O-])=O)O1)OCC2=CC=C(CN3C(C(C4=C3C(Br)=CC(Br)=C4)=O)=O)C=C2
Molecular Formula
C21H12Br2N2O7
Molecular Weight
564.14
References & Citations
[1]Gowda K, et al. Identification of Novel Isatin Derivative Bearing a Nitrofuran Moiety as Potent Multi-Isoform Aldehyde Dehydrogenase Inhibitor. Molecules. 2024 Jun 29;29 (13) :3114.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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