AMG7703
AMG7703 is a selective and allosteric agonists of FFA2 (GPR43), the receptor for short-chain fatty acids (SCFAs), acetate, and propionate. AMG7703 can be used to research for in inflammatory and metabolic[1].
Product Specifications
CAS Number
[1103523-24-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Free Fatty Acid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/amg7703.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1=NC=CS1)[C@H](C2=CC=C(Cl)C=C2)C(C)C
Molecular Formula
C14H15ClN2OS
Molecular Weight
294.80
Precautions
H302, H315, H319, H335
References & Citations
[1]Lee T, et al. Identification and functional characterization of allosteric agonists for the G protein-coupled receptor FFA2. Mol Pharmacol. 2008 Dec. 74 (6) :1599-609.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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