Q-VD-OPh
Q-VD-OPh is an irreversible pan-caspase inhibitor with potent antiapoptotic properties; inhibits caspase 7 with an IC50 of 48 nM and 25-400 nM for other caspases including caspase 1, 3, 8, 9, 10, and 12. Q-VD-OPh can inhibits HIV infection. Q-VD-OPh is able to cross the blood-brain barrier.
Product Specifications
CAS Number
1135695-98-5
Product Name Alternative
QVD-OPH; Quinoline-Val-Asp-Difluorophenoxymethylketone
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Caspase; HIV
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/Q-VD-OPh.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)C[C@H](NC([C@@H](NC(C1=NC2=CC=CC=C2C=C1)=O)C(C)C)=O)C(COC3=C(F)C=CC=C3F)=O
Molecular Formula
C26H25F2N3O6
Molecular Weight
513.49
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Caspase 1; Caspase 10; Caspase 12; Caspase 3; Caspase 7; Caspase 8; Caspase 9
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
