FC131
Product Specifications
UNSPSC Description
FC131 is a potent CXCR4 antagonist. FC131 inhibits [125I]-SDF-1 binding to CXCR4 with an IC50 of 4.5 nM. FC131 has anti-HIV activity[1].
Target Antigen
CXCR; HIV
Type
Peptides
Related Pathways
Anti-infection;GPCR/G Protein;Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/fc131.html
Solubility
H2O
Smiles
O=C([C@@H](NC([C@@H](NC([C@@H](CC1=CC=C(O)C=C1)NC(CNC2=O)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)N[C@H]2CC3=CC4=C(C=CC=C4)C=C3
Molecular Weight
729.83
References & Citations
[1]Tamamura H, et al. Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131. J Med Chem. 2005 Jan 27;48(2):380-91.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1104/FC131-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1104/
Clinical Information
No Development Reported
CAS Number
606968-52-9
Curated Selection
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