Boc-C5-O-C5-O-C6-Cl
Boc-C5-O-C5-O-C6-Cl (PROTAC Linker 2) is a PROTAC linker utilized to connect the respective tyrosine kinase inhibitor (TKI) to the E3 recruiting ligand.
Product Specifications
CAS Number
[1835705-52-6]
Product Name Alternative
PROTAC Linker 2
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/PROTAC_Linker_2.html
Concentration
10mM
Purity
95.0
Solubility
10 mM in DMSO
Smiles
O=C(OC(C)(C)C)CCCCCOCCCCCOCCCCCCCl
Molecular Formula
C21H41ClO4
Molecular Weight
393.00
Precautions
H302, H315, H319, H335
References & Citations
[1]Lai AC, et al. Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL. Angew Chem Int Ed Engl. 2016 Jan 11;55 (2) :807-10.|[2]ARYL SULFONOHYDRAZIDES. US 20170121321 A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers
Available Sizes
Curated Selection
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