3- (Trifluoromethyl) benzaldehyde

3- (Trifluoromethyl) benzaldehyde is a key intermediate in organic synthesis. 3- (Trifluoromethyl) benzaldehyde can be used to synthesize 2,3-di- and 2,2,3-trisubstituted-3-methoxycarbonyl-γ-butyrolactones. 3- (Trifluoromethyl) benzaldehyde derivatives have antitumor effects against nasopharyngeal carcinoma, leukemia, and breast cancer[1][2].

Product Specifications

CAS Number

[454-89-7]

UNSPSC

12352005

Hazard Statement

H227, H315, H319, H335, H400, H411

Target

Drug Intermediate

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/3-trifluoromethyl-benzaldehyde.html

Purity

99.83

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC(F)(F)C1=CC(C([H])=O)=CC=C1

Molecular Formula

C8H5F3O

Molecular Weight

174.12

Precautions

H227, H315, H319, H335, H400, H411

References & Citations

[1]Le Floch C, et al. Synthesis of 2,3-di- and 2,2,3-trisubstituted-3-methoxycarbonyl-γ-butyrolactones as potent antitumor agents. Eur J Med Chem. 2015 Jan 7;89:654-70.|[2]Kitazume T, et al. Synthesis of fluorinated materials catalyzed by proline or antibody 38C2 in ionic liquid. Journal of fluorine chemistry, 2003, 121 (2) : 205-212.