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Rozibafusp alfa

Rozibafusp alfa (AMG-570) is a humanized IgG2-κ monoclonal antibody targets ICOSL and BAFF. Prezalumab demonstrates beneficial activities on the arthritis of systemic lupus erythematosus. Prezalumab can be used for the research of sjogren's syndrome cutaneous lupus erythematosus, psoriasis and systemic lupus erythematosus (SLE) [1][2].

Product Specifications

CAS Number

2143449-47-0

Product Name Alternative

AMG-570

UNSPSC

12352203

Target

CD28; TNF Receptor

Type

Inhibitory Antibodies

Related Pathways

Apoptosis; Immunology/Inflammation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/rozibafusp-alfa.html

Solubility

10 mM in DMSO

Smiles

[Rozibafuspalfa]

References & Citations

[1]Rozibafusp alfa. IMGT.|[2]Zhang M, et al. Development of an ICOSL and BAFF bispecific inhibitor AMG 570 for systemic lupus erythematosus treatment. Clin Exp Rheumatol. 2019 Nov-Dec;37 (6) :906-914.

Shipping Conditions

Room temperature

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Frequently Asked Questions

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