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ETP-46321

Product Specifications

UNSPSC Description

ETP-46321 is a potent and orally bioavailable PI3Kα and PI3Kδ inhibitor with Kiapps of 2.3 and 14.2 nM, respectively.

Target Antigen

PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/etp-46321.html

Purity

99.34

Solubility

DMSO : ≥ 33 mg/mL

Smiles

NC(N=C1)=NC=C1C2=CN3C=C(CN4CCN(S(=O)(C)=O)CC4)N=C3C(N5CCOCC5)=N2

Molecular Weight

473.55

References & Citations

[1]Martínez González S, et al. Identification of ETP-46321, a potent and orally bioavailable PI3K α, δ inhibitor. Bioorg Med Chem Lett. 2012 May 15;22(10):3460-6.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-12340/ETP-46321-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-12340/ETP-46321-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1252594-99-2

Available Sizes

Curated Selection

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