Validamine
Product Specifications
UNSPSC Description
Validamine competitively inhibits β-glucosidase in a pH-dependent and dose-dependent manner, with an IC50 value of 2.92mM, and the maximum inhibitory ability is at the optimum pH value of this enzyme[1].
Target Antigen
Glycosidase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/validamine.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@H]([C@@H]([C@@H](O)[C@@H](N)C1)O)O
Molecular Weight
177.20
References & Citations
[1]Takeuchi M, et al. Inhibitory effect of validamine, valienamine and valiolamine on activities of carbohydrases in rat small intestinal brush border membranes. Chem Pharm Bull (Tokyo). 1990 Jul;38(7):1970-2.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N2383/Validamine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N2383/
Clinical Information
No Development Reported
CAS Number
32780-32-8
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