Lamifiban
Lamifiban is a nonpeptide glycoprotein IIb/IIIa receptor and platelet aggregation antagonist. Lamifiban in combination with thrombolytic therapy effectively restores coronary arterial patency. Lamifiban is promising for research of acute coronary syndromes[1].
Product Specifications
CAS Number
144412-49-7
Product Name Alternative
Ro 44-9883
UNSPSC
12352005
Target
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/lamifiban.html
Smiles
O=C(O)COC1CCN(C([C@@H](NC(C2=CC=C(C(N)=N)C=C2)=O)CC3=CC=C(O)C=C3)=O)CC1
Molecular Formula
C24H28N4O6
Molecular Weight
468.50
References & Citations
[1]Moliterno DJ, et al. Randomized, Placebo-Controlled Study of Lamifiban with Thrombolytic Therapy for the Treatment of Acute Myocardial Infarction: Rationale and Design for the Platelet Aggregation Receptor Antagonist Dose Investigation and Reperfusion Gain in Myocardial Infarction (PARADIGM) Study. J Thromb Thrombolysis. 1995;2 (3) :165-169.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
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