Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Koumine (Standard)

Koumine (Standard) is the analytical standard of Koumine. This product is intended for research and analytical applications. Koumine is an alkaloid separated from Gelsemium elegans, shows potent anti-tumor activity. Koumine up-regulates the Bax/Bcl-2 ratio and caspase-3 expression in human breast cancer cells[1]. Koumine has anxiolytic, antistress, antipsoriatic, and analgesic activities[3], protects against the development of arthritis in Rheumatoid arthritis (RA) animal models[2].

Product Specifications

CAS Number

1358-76-5

UNSPSC

12352005

Target

Bcl-2 Family; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; Others

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/koumine-standard.html

Smiles

C=C[C@]12[C@]3([H])C[C@@H]4C5=NC6=CC=CC=C6[C@@]51C[C@H](N(C)C2)[C@@]3([H])CO4

Molecular Formula

C20H22N2O

Molecular Weight

306.40

References & Citations

[1]Zhang X, et al. Apoptotic Effect of Koumine on Human Breast Cancer Cells and the Mechanism Involved. Cell Biochem Biophys. 2015 Jun;72 (2) :411-6.|[2]Yang J, et al. Effects of Koumine on Adjuvant- and Collagen-Induced Arthritis in Rats. J Nat Prod. 2016 Oct 28;79 (10) :2635-2643.|[3]Jin GL, et al. Koumine Attenuates Neuroglia Activation and Inflammatory Response to Neuropathic Pain. Neural Plast. 2018 Mar 25;2018:9347696.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

U2AF1L5 (Center) Rabbit Polyclonal Antibody
AP12454PU-N 400 µL

U2AF1L5 (Center) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
RPL3 (NM_001033853) Human Over-expression Lysate
LC422420 20 µg

RPL3 (NM_001033853) Human Over-expression Lysate

Sign In for Pricing
View Details
G3BP-1 (Ab-232) Antibody
8B7089-AAT 50 µg

G3BP-1 (Ab-232) Antibody

Sign In for Pricing
View Details
Isovalerylcarnitine-d9
TRC-I238061-10MG 10 mg

Isovalerylcarnitine-d9

Sign In for Pricing
View Details
Mouse Cdc7 activation kit by CRISPRa
GA200654 1 Kit

Mouse Cdc7 activation kit by CRISPRa

Sign In for Pricing
View Details
Cytokeratin-19 Antibody
KC-284-01 50 μL

Cytokeratin-19 Antibody

Sign In for Pricing
View Details