AZD-6605
AZD-6605 is a potent, reversible inhibitor of MMP2, MMP9, MMP12 and MMP13 with excellent selectivity. During drug development, AZD-6605 was optimized for activity, solubility and DMPK properties against MMP13 by replacing the zinc hydroxide binding group associated with historical inhibitors[1].
Product Specifications
CAS Number
893556-15-5
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/azd-6605.html
Smiles
O=C1NC([C@](C)(N1)CS(=O)(N2CCC(CC2)OC3=CC=C(C=C3)OC(F)(C(F)F)F)=O)=O
Molecular Formula
C18H21F4N3O6S
Molecular Weight
483.43
References & Citations
[1]Hydantoin based inhibitors of MMP13--discovery of AZD6605
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog