AZD-6605
AZD-6605 is a potent, reversible inhibitor of MMP2, MMP9, MMP12 and MMP13 with excellent selectivity. During drug development, AZD-6605 was optimized for activity, solubility and DMPK properties against MMP13 by replacing the zinc hydroxide binding group associated with historical inhibitors[1].
Product Specifications
CAS Number
893556-15-5
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/azd-6605.html
Smiles
O=C1NC([C@](C)(N1)CS(=O)(N2CCC(CC2)OC3=CC=C(C=C3)OC(F)(C(F)F)F)=O)=O
Molecular Formula
C18H21F4N3O6S
Molecular Weight
483.43
References & Citations
[1]Hydantoin based inhibitors of MMP13--discovery of AZD6605
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940296-100 1x 100 µL
Blood Group Antigen B (CD173) (HEB-20), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC881129-500 1x 500 µL
MHC II (HLA-DP) (beta chain) (Bra-14), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
RDR-HDAC1-Hu-01 96 Tests
Human Histone Deacetylase 1 (HDAC1) ELISA Kit
Sign In for Pricing
View Details