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MAC-0547630

MAC-0547630 is a potent inhibitor of undecaprenyl diphosphate synthase (UppS), with IC50s of 0.05 μM and 1.6 μM for UppSBS and UppSBA, respectively. MAC-0547630 is active against B. subtilis in vitro (MIC 0.1 ng/mL) [1].

Product Specifications

CAS Number

950386-41-1

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/mac-0547630.html

Smiles

FC1=CC=C(C2=C(N=C(C)C=C3N4CCCCCC4)N3N=C2)C=C1

Molecular Formula

C19H21FN4

Molecular Weight

324.40

References & Citations

[1]Tomasz L Czarny, et al. A Small-Molecule Screening Platform for the Discovery of Inhibitors of Undecaprenyl Diphosphate Synthase. ACS Infect Dis. 2016 Jul 8;2 (7) :489-99.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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