Human CD45 / PTPRC protein, His Tag

CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 62.8 kDa. The protein migrates as 120-170 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

P08575-3

Expression Region

Gln 26 - Lys 577

Host

HEK293

Target

CD45

Conjugation

Unconjugated

Tag

C-10xHis

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

62.8 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Storage Conditions

-20°C

Package Size

500ug*2

Host or Source

HEK293

Species

Human

Protein ID

P08575-3

Preservative

Trehalose

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS1260511-01 0.02 mg (E-Coli)

Recombinant Neisseria meningitidis serogroup C/serotype 2a Ribosome maturation factor RimM (rimM)

Ask

View Details

MBS1260511-02 0.1 mg (E-Coli)

Recombinant Neisseria meningitidis serogroup C/serotype 2a Ribosome maturation factor RimM (rimM)

Ask

View Details

MBS1260511-03 0.02 mg (Yeast)

Recombinant Neisseria meningitidis serogroup C/serotype 2a Ribosome maturation factor RimM (rimM)

Ask

View Details

MBS1260511-04 0.1 mg (Yeast)

Recombinant Neisseria meningitidis serogroup C/serotype 2a Ribosome maturation factor RimM (rimM)

Ask

View Details

MBS1260511-05 0.02 mg (Baculovirus)

Recombinant Neisseria meningitidis serogroup C/serotype 2a Ribosome maturation factor RimM (rimM)

Ask

View Details

MBS1260511-06 0.02 mg (Mammalian-Cell)

Recombinant Neisseria meningitidis serogroup C/serotype 2a Ribosome maturation factor RimM (rimM)

Ask

View Details