GSK-3β inhibitor 19
GSK-3β inhibitor 19 (compound 36) is a GSK-3β inhibitor, with IC50 of 70 nM. GSK-3β inhibitor 19 can be used in anti-inflammatory and Alzheimer's disease related research[1].
Product Specifications
UNSPSC
12352005
Target
GSK-3
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR; Stem Cell/Wnt
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gsk-3β-inhibitor-19.html
Smiles
O=C(C1CC1)NC2=NC=CC(C3=CC=C(C4=NOC=N4)S3)=C2
Molecular Formula
C15H12N4O2S
Molecular Weight
312.35
References & Citations
[1]Góral I, et al. Exploring Novel GSK-3β Inhibitors for Anti-Neuroinflammatory and Neuroprotective Effects: Synthesis, Crystallography, Computational Analysis, and Biological Evaluation. ACS Chem Neurosci. 2024 Sep 4;15 (17) :3181-3201.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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