ML406
ML406 is a small molecule probe that shows anti-tubercular activity via M.tuberculosis BioA (DAPA synthase) enzyme inhibition with an IC50 of 30 nM. M.tuberculosis BioA is an enzyme involved in biotin biosynthesis in M.tuberculosis[1].
Product Specifications
CAS Number
774589-47-8
UNSPSC
12352005
Hazard Statement
H410
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ml406.html
Purity
99.05
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C1=CC=C(N2CCN(C(C3=CC=C(OCO4)C4=C3)=O)CC2)C=C1)=O
Molecular Formula
C20H20N2O4
Molecular Weight
352.38
Precautions
H410
References & Citations
[1]Casalena D, et al. Discovery of small molecule probe that shows anti-tubercular activity via Mtb bioA (DAPA synthase) enzyme inhibition. 2014 Apr 15 [updated 2015 Jan 16]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD) : National Center for Biotechnology Information (US) ; 2010–.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Des[N-[(1S)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]carboxamido] 1-Carboxy Telaprevir](https://cdn.genprice.uk/products/572/4600646667345/imageurl/trc-d288915-5mg.webp)
TRC-D288915-5MG 5 mg
Des[N-[(1S)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]carboxamido] 1-Carboxy Telaprevir
Sign In for Pricing
View Details 
![RPL7A Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4D5]](https://cdn.genprice.uk/products/937/6868c40a994c49e6dc4054ea/imageurl/ta811794am.webp)
TA811794AM 100 µL
RPL7A Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4D5]
Sign In for Pricing
View Details ![CALR Rabbit Monoclonal Antibody [Clone ID: 23GB700]](https://cdn.genprice.uk/products/937/6868c300994c49e6dc3ecc49/imageurl/ta424579.webp)
TA424579 100 µL
CALR Rabbit Monoclonal Antibody [Clone ID: 23GB700]
Sign In for Pricing
View Details 