Ganoderenic acid K
Ganoderenic acid K is a natural product, that can be isolated from fruiting bodies of Ganoderma lucidum. Ganoderenic acid K shows strong inhibitory activity against HMG-CoA reductase (HMGCR) with IC50 of 16.5 μM[1].
Product Specifications
CAS Number
[942950-94-9]
UNSPSC
12352211
Target
HMG-CoA Reductase (HMGCR)
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ganoderenic-acid-k.html
Purity
99.64
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@]([C@@H](C(C3=C1[C@H](C[C@]4([H])[C@@]3(CC[C@@H](C4(C)C)O)C)O)=O)OC(C)=O)([C@H](CC2=O)/C(C)=C/C(CC(C)C(O)=O)=O)C
Molecular Formula
C32H44O9
Molecular Weight
572.69
References & Citations
[1]Chen B, et al. Triterpenes and meroterpenes from Ganoderma lucidum with inhibitory activity against HMGs reductase, aldose reductase and α-glucosidase. Fitoterapia. 2017 Jul;120:6-16.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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