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Plasma kallikrein-IN-4

Plasma kallikrein-IN-4 (Example 153) is a plasma kallikrein inhibitor with an IC50 of 0.016 μM against human plasma kallikrein[1].

Product Specifications

CAS Number

1357954-34-7

UNSPSC

12352005

Target

Kallikrein

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/plasma-kallikrein-in-4.html

Purity

98.61

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CN(CC2=CC3=C(N=C(C)C=C3)C=C2)N=N1)NCC4=C(C)C=C(N)N=C4C

Molecular Formula

C22H23N7O

Molecular Weight

401.46

References & Citations

[1]Trixi Brandl, et al. N- ((6-amino-pyridin-3-yl) methyl) -heteroaryl-carboxamides as inhibitors of plasma kallikrein. Patent WO2012017020A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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