Plasma kallikrein-IN-4
Plasma kallikrein-IN-4 (Example 153) is a plasma kallikrein inhibitor with an IC50 of 0.016 μM against human plasma kallikrein[1].
Product Specifications
CAS Number
1357954-34-7
UNSPSC
12352005
Target
Kallikrein
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/plasma-kallikrein-in-4.html
Purity
98.61
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CN(CC2=CC3=C(N=C(C)C=C3)C=C2)N=N1)NCC4=C(C)C=C(N)N=C4C
Molecular Formula
C22H23N7O
Molecular Weight
401.46
References & Citations
[1]Trixi Brandl, et al. N- ((6-amino-pyridin-3-yl) methyl) -heteroaryl-carboxamides as inhibitors of plasma kallikrein. Patent WO2012017020A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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