N-Formyl-MMYALF (TFA)
N-Formyl-MMYALF TFA is a mitochondrial N-formyl peptide that has the activity of depleting calcium ions in the endoplasmic reticulum. N-Formyl-MMYALF TFA can inhibit the FPR-1-mediated chemotactic response of PMNs to bacterial peptides[1].
Product Specifications
UNSPSC
12352209
Target
Formyl Peptide Receptor (FPR)
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/n-formyl-mmyalf-tfa.html
Purity
99.59
Smiles
OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)=O)NC([C@H](CCSC)NC([C@@H](NC=O)CCSC)=O)=O.O=C(O)C(F)(F)F.[x]
Molecular Formula
C38H54N6O9S2.xC2HF3O2
Molecular Weight
803.00 (free base)
References & Citations
[1]Kwon W Y, et al. Circulating mitochondrial N-formyl peptides contribute to secondary nosocomial infection in patients with septic shock[J]. Proceedings of the National Academy of Sciences, 2021, 118 (17) : e2018538118.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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